Which clinical sign is associated with hyperglycemia?

Increased urination is a clinical sign associated with hyperglycemia due to the body's response to elevated blood sugar levels. When blood glucose becomes excessively high, the kidneys attempt to remove the extra glucose by filtering it from the blood and excreting it through urine. This process leads to osmotic diuresis, where water is drawn into the urine, resulting in a higher volume of urination. As fluid is lost through frequent urination, the body often becomes dehydrated, which can further exacerbate the state of hyperglycemia if not adequately managed.

The other options do not typically correlate with hyperglycemia. Decreased appetite is more commonly associated with hypoglycemia or specific conditions rather than high blood sugar levels. Skin rashes can arise from various causes but are not directly linked to hyperglycemia. Low blood pressure is generally not a sign of hyperglycemia; in fact, dehydration from excessive urination can eventually contribute to lower blood pressure in severe cases, but it is not a direct symptom of high blood sugar.